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Can Bryan Johnson Actually Cheat Death?

The Anti-Aging Protocol Built to Keep Him Alive as Long as Possible

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Hello Health Nerds,

This week, we’re exploring Bryan Johnson’s ambitious Blueprint Protocol, the anti-aging experiment pushing the boundaries of human health and lifespan. From strict dietary precision to advanced medical tracking, his routine is engineered for peak performance inside and out. Guided by science and executed with unwavering discipline, his approach blends cutting-edge technology with relentless consistency to pursue one goal, which is living longer, better, and stronger.

If you’ve ever woken up feeling like this frog, you already understand why Bryan Johnson spends millions to slow aging.

In this week’s newsletter, we explore:

Inside Bryan Johnson’s Blueprint System

Bryan Johnson’s Blueprint Protocol is a structured approach to health designed to optimize both lifespan and quality of life. Instead of relying on guesswork, it uses precise measurements and proven strategies to align the body with its best possible state.

  • Core focus on longevity: The system prioritizes key health areas like nutrition, exercise, sleep, skin care, and mental well-being, ensuring each habit supports long-term wellness.

  • Data-driven design: He tracked the biological age of dozens of organs and used the findings to refine his plan, making adjustments until consistent, measurable improvements were seen.

  • Clear metrics and sustainability: Guided by indicators like inflammation levels, sleep quality, and metabolic function, the diet, supplements, and daily habits are built to work long-term without constant changes.

  • Shaped by years of testing: Ongoing research and analysis turned the Blueprint into a repeatable, evidence-based system with results that can be tracked over time.

The Blueprint isn’t just a plan, it’s a disciplined lifestyle built to slow aging and keep the body performing at its peak.

Why the Blueprint Protocol Stands Out

The Blueprint isn’t just theory, it’s a living experiment built on years of tracking, testing, and refining. Every method was chosen for its proven impact on health and longevity.

  • Science-led selection: A deep review of longevity research identified the most effective strategies, then ranked them based on measurable results.

  • Precision tracking: He measured over 70 organs repeatedly to understand progress, make adjustments, and keep improvements on track.

  • High-performance health markers: Continuous refinement helped achieve top-tier results in areas like cardiovascular function, inflammation reduction, and liver health.

  • Open-source approach: Findings, routines, and data are shared publicly so anyone can follow and adapt the protocol for their own goals.

This system proves what’s possible when health is approached with discipline, evidence, and full transparency.

Why Bryan Johnson Built the Blueprint

The Blueprint started as a personal mission, driven by Bryan’s own health struggles and a desire to rethink how we approach aging and longevity. Over time, it evolved into a system anyone could follow.

  • Questioning aging itself: He set out to see if consistent, science-backed actions could slow or delay the effects of aging.

  • From personal need to structured plan: His own mental and physical challenges led him to design a routine grounded in measurable, lasting improvements.

  • A guide others can trust: By cutting through conflicting health advice, he created a system with clear steps that could be applied for years to come.

  • Knowing where you stand: He believes the first step in fighting aging is understanding your body’s current state because you can’t improve what you don’t measure.

What began as a way to regain control over his health became a framework for challenging limits, starting with knowing exactly how your body is aging.

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Bryan Johnson’s Daily Blueprint

Bryan Johnson’s day is designed around habits that support longevity, using structure, consistency, and science-backed choices from morning to night.

  • Sleep as a priority: In bed by 8:30 p.m., keeping his room cool, dark, and quiet to improve rest, recovery, and mental clarity.

  • Morning start: Wakes around 5 a.m. for breathwork, meditation, light exposure, and red light therapy, followed by a collagen-protein drink for hydration and recovery.

  • Training and breakfast: 60–90 minutes of exercise focused on flexibility, balance, and strength, then a nutrient-rich breakfast with protein, healthy fats, and antioxidants.

  • Targeted supplements: Takes a structured stack including vitamins, antioxidants, omega-3s, gut health boosters, and compounds for cardiovascular, liver, and metabolic support.

  • Focused work blocks: Starts deep work at 7:45 a.m., with nutrient-dense meals like a veggie bowl mid-morning and a final meal by 11 a.m. for long-lasting energy.

  • Evening wind-down: Limits liquids after 4 p.m., spends time walking or with family, and follows a calming night routine before sleeping.

You can read our Bryan Johnson’s Daily Routine article for a full breakdown of his daily schedule, including his morning habits, workouts, and wellness practices.

Bryan Johnson’s Supplement Stack

Bryan Johnson’s supplements are scheduled by time of day and targeted to support brain health, energy, inflammation control, and cellular repair. Each choice fits into his larger Blueprint approach to aging well.

  • Morning start: Begins with a multi-ingredient nutrient blend designed to enhance memory, support physical recovery, and improve overall energy production. He follows this with collagen to aid joint health and skin elasticity, creatine for muscle and mental performance, and gut-friendly prebiotics to boost digestion and maintain a balanced microbiome.

  • With meals: Incorporates plant protein to help rebuild and maintain lean muscle, paired with healthy fats and antioxidants for inflammation control and cell protection. Omega-3 supplements further promote cardiovascular health and cognitive function, ensuring sustained energy and focus throughout the day.

  • Specialized compounds: Uses targeted formulas like antimicrobials for immune resilience, anti-inflammatory blends for joint and tissue recovery, and carefully chosen vitamins for optimal cardiovascular, metabolic, and neurological health. Each is measured for maximum benefit without unnecessary excess.

  • Evening support: Ends the day with a combination of omega-3s to maintain fatty acid balance, iron for stable oxygen levels, antioxidants to counter cellular damage, and a sleep-regulating aid to promote deep, restorative rest. This ensures the body is primed for recovery overnight.

We’ve broken down every supplement he takes and the exact timing behind it in our Bryan Johnson Supplement List article.

Bryan Johnson’s Diet Plan

Bryan Johnson’s eating plan focuses on timing, nutrient density, and quality rather than restriction. Each meal is carefully designed to support energy levels, digestion, and long-term health while helping slow the aging process.

  • Precise calorie and macro targets: Consumes around 2,250 calories daily with a macro split of roughly 25% protein, 35% carbohydrates, and 40% fat, calibrated to support muscle repair, hormone balance, and steady energy.

  • Clean ingredient focus: Completely avoids added sugars, seed oils, fried foods, alcohol, and processed products to reduce inflammation and stabilize blood sugar.

  • Structured morning routine: Starts the day at 5:25 a.m. with a nutrient-rich drink containing fiber, protein, and gut-friendly compounds, followed by a high-protein, antioxidant-rich breakfast at 6:45 a.m. to enhance focus and muscle maintenance.

  • Balanced mid-morning and final meals: A 9:00 a.m. plate of lentils, cruciferous vegetables, and mushrooms delivers fiber and antioxidants, while an 11:00 a.m. bowl of sweet potatoes, chickpeas, avocado, and fermented vegetables ensures sustained energy and digestive support.

  • Heart-healthy additions: Uses olive oil, vinegar, and other anti-inflammatory ingredients to improve cardiovascular health, nutrient absorption, and recovery.

  • Strict eating window: No snacks between meals to support insulin sensitivity, encourage autophagy, and allow the digestive system to reset.

You can see his full eating plan, including exact meals, timing, and nutrition breakdown, in our Bryan Johnson Diet Routine article.

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Bryan Johnson’s Workout Strategy

For Bryan Johnson, training is an important part of the Blueprint Protocol. It is not just for fitness, but also a way to protect long-term health and slow biological aging. His approach combines strength, cardio, mobility, and active recovery so his body stays strong and resilient throughout the year.

  • Weekly plan with purpose: He follows a six-day routine, alternating three days of strength training with three days of cardio. This structure supports muscle growth, cardiovascular health, and endurance while ensuring no single system is overworked.

  • Smart intensity and variety: Each week includes 150 minutes of moderate activity and 75 minutes of higher-intensity exercise. Flexibility and mobility work are also built in to improve balance, reduce injury risk, and enhance overall movement quality.

  • Daily activity built in: In addition to structured workouts, he focuses on movement throughout the day by walking or stretching for 5 to 10 minutes after meals and breaking up long sitting periods every half hour to maintain circulation and joint health.

  • Safe and adaptable training: Exercises are selected for maximum benefit with minimal risk, and adjustments are made for different needs, such as tailoring the cardio and strength balance for women based on hormonal phases or postmenopausal health goals.

If you want a deeper look into the exact exercises, weekly schedule, and training principles he follows, we have a detailed breakdown in our Bryan Johnson Workout Routine article.

Bryan Johnson’s Sleep Plan

For Bryan Johnson, sleep is the anchor for his entire Blueprint Protocol. He treats it as a skill to master, building habits that help the body recover, the brain perform better, and energy remain steady throughout the day.

  • Making rest a priority: He designs his day around sleep rather than fitting sleep in when everything else is done. This mindset allows him to protect his bedtime and wake-up time as non-negotiable parts of his schedule.

  • A calm and consistent wind-down: Evenings include low-stimulation activities such as light stretching, breathwork, warm baths, or soft music to signal the body that it is time to rest. Lights are dimmed, screens are avoided, and warm or red light is preferred in the hours before bed.

  • Optimizing the sleep environment: His bedroom is kept cool between 60 and 67°F with breathable bedding and good airflow. It is dark, quiet, and distraction-free, often supported by blackout curtains and white noise or earplugs when needed.

  • Daily habits that support quality rest: He sticks to a 7 to 9-hour sleep schedule every night, finishes meals at least two hours before bed, limits caffeine and alcohol for 10 hours before sleeping, and uses morning sunlight exposure to help regulate his circadian rhythm.

These habits show how a structured sleep routine can transform both physical and mental performance. For an in-depth look at his nighttime rituals, bedroom setup, and data-tracking methods, read our Bryan Johnson Sleep Routine article.

Hair Loss Prevention Strategy

Bryan Johnson approaches hair care with a focus on prevention, internal nourishment, and daily consistency. Rather than waiting for visible thinning, he built a plan that addresses scalp and hair health from multiple angles.

  • Addressing the issue early and maintaining consistency: He began tackling hair loss in his late 20s, years before it became obvious. Through decades of commitment, he has sustained a healthy, full head of hair well into his 40s.

  • Combining internal and external treatments: His longevity supplement stack contains key nutrients such as Omega-3 fatty acids, Biotin, Vitamin D, Vitamin C, Zinc, and Iron, which promote both hair growth and scalp health. Alongside this, he uses a topical scalp solution twice daily, massaged in with a silicone scrubber to stimulate circulation and improve absorption of active ingredients.

  • Personalizing care based on data: Lab testing and genetic analysis guide his topical formula, ensuring he uses only the most effective ingredients for his biology. He also incorporates red light therapy twice a day to energize hair follicles and support healthy scalp circulation.

  • Exploring treatments with caution: Johnson uses low-dose oral medications to maintain hair density, introducing them gradually to monitor for side effects. He also experiments with advanced regrowth techniques but only after tracking measurable results to ensure effectiveness before making them a long-term habit.

This routine shows how proactive, data-informed care can make a lasting difference in hair health. If you want the complete breakdown of his product choices, tools, and tracking process, check out our Bryan Johnson Hair Care Routine article.

Oral Care Plan

Bryan Johnson’s oral health routine is built around small but highly consistent steps that protect both function and appearance over the long term. Each habit works together to support gum health, maintain enamel, and keep the mouth free of harmful bacteria.

  • Rinsing and flossing for a clean foundation: Each morning and evening begins with a high-pressure water flosser to remove food particles, plaque, and bacteria from between the teeth and along the gumline. This is followed by flossing, which gets into tighter spaces the flosser cannot fully reach, further improving gum health and lowering inflammation.

  • Brushing and toothpaste rotation: He uses a soft-bristle toothbrush twice a day to protect enamel while still cleaning effectively. He rotates between two fluoride-free toothpaste formulas to cover a wider range of oral needs, including sensitivity, freshness, and bacteria control.

  • Targeted cleaning tools for freshness: His routine includes using a tongue scraper to reduce bacteria buildup and keep breath fresh. After brushing, he finishes with a gentle, alcohol-free mouthwash to remove remaining bacteria without drying the mouth.

  • Supportive treatments and prevention: In earlier stages of improving his oral health, he occasionally used diluted tea tree oil as an antibacterial rinse. Today, he also wears a nighttime device to protect against enamel wear from teeth grinding and to promote proper jaw alignment. Regular dental checkups twice a year ensure that any potential issues are caught and addressed early.

By combining daily discipline with preventive care, this plan helps keep his oral health strong year after year. You can explore every detail of his tools, techniques, and dentist-recommended practices in our Bryan Johnson Oral Care Routine article.

Skin Maintenance Strategy

For Bryan Johnson, skincare is more than surface-level appearance. It’s a methodical approach to track biological age, manage inflammation, and slow visible signs of aging. By combining protective habits with targeted nutrition and treatments, he aims to keep his skin healthy and resilient for decades.

  • Sun exposure and protection balance: He schedules time outdoors in the morning or late afternoon to gain the benefits of natural light, such as mood enhancement and vitamin D production, while avoiding peak hours to limit UV-related skin damage. On sunny days, he adds hats, UV-blocking clothing, and mineral sunscreen to further protect against collagen breakdown and premature aging.

  • Nourishment for skin repair: His diet is rich in whole, unprocessed foods to support skin clarity, prevent breakouts, and provide nutrients essential for collagen synthesis. He limits fried and processed foods that can trigger excess oil production and dullness, and includes collagen peptides, niacinamide, and vitamin C to promote elasticity, hydration, and even tone.

  • Hydration from within and without: Oral hyaluronic acid supplements help his skin retain moisture and improve texture, while topical products like retinoids, vitamin C, and hyaluronic acid serums work on the outer layer for smoother, firmer results.

  • Preventive and restorative treatments: Broad-spectrum sunscreen is applied daily to prevent UV damage, while imaging tools track changes in pigmentation, texture, and collagen density to guide future skincare choices. Red light therapy and occasional advanced treatments, such as microneedling, are used thoughtfully to boost collagen production and repair.

This careful balance of lifestyle, nutrition, and targeted treatments forms a skin care approach that’s both proactive and measurable. For a detailed look at every step, including his go-to products and how he tracks progress, explore our Bryan Johnson Skin Care Routine article.

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Bryan Johnson’s Daily Routine for Longevity 
Bryan Johnson’s day is built around precision and science, from his early wake-up and nutrient-rich meals to his strict sleep schedule and exercise plan. Every habit is measured and tracked, all aimed at slowing the aging process. If you want to see how one of the most disciplined people on the planet structures his life for health and performance, this breakdown is worth reading.

Bryan Johnson’s Supplement List for Anti-Aging 
From antioxidants to gut health boosters, Bryan Johnson’s supplement stack is carefully designed to optimize his mind and body. Each choice is backed by research and integrated into his Blueprint Protocol for maximum effect. If you’re curious about the science behind his anti-aging approach, this detailed guide shows exactly what’s in his daily stack and why.

Want to Take Control of Your Health?

Bryan Johnson’s Blueprint isn’t about quick fixes, it’s about consistency, measurement, and proven strategies that work over time. If you want to cut through the noise and start building habits that actually improve your energy, focus, and longevity, join our community on Facebook and follow us on Instagram. We share actionable, science-based tips to help you stay motivated, track your progress, and see results you can measure.

Lasting change doesn’t happen by accident. It happens when you commit to routines that work.

The Routines Team

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